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The principal cytochrome P450 isoenzyme involved seems to get CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Around eighty five% of the oral dose seems during the urine inside 24 several hours of administration, most given that the glucuronide conjugate, with tiny amounts of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity detail